Dr. Fang Wang Global Blood Therapeutics, USA Abstract: In light of the balancing act among quality, speed, and cost, collaborative partnering between pharmaceutical companies and contract research/manufacturing organizations is becoming increasingly important in meeting our goals of delivering high quality APIs and drug products to patients. This talk will summarize the challenges the pharmaceutical industry is facing today and will continue to face in the future in the area of API crystallization engineering and manufacturing. In addition, various strategies will be discussed to overcome the challenges in order to deliver high quality therapies to patients quickly and cost effectively. Case studies will be provided to illustrate the strategies. Ultimately an effective model of partnering to meet patient’s needs will be presented.