Dr. Jian Wang is an expert in API crystallization, with comprehensive knowledge of the science and technologies required to meet the needs of small molecule drug development. She has over 30 years of R&D experience in API crystallization and reaction engineering, and has been providing R&D services since 2005 to pharmaceutical clients around the globe.
Dr. Wang received her Ph.D. degree in Chemical Engineering in 1994, from the University of Pittsburg with Prof. Donna Blackmond and Prof. Irving Winder. She published 20 peer-reviewed articles and 6 patents (5 related to API crystallization) before getting into technical services.
During her 11-year tenure at Merck since 1994, Jian became an expert in API process R&D and a champion in implementing science-based and technology-enabled approaches. She promoted the application of PAT tools in process R&D serving as a consultant at Mettler Toledo AutoChem during 2005-2010. In 2011-2013, Jian took the responsibility as VP of Crystallization Development at Crystal Pharmatech, helping a diverse client base in solving API crystallization problems. To better assist new drug development programs, Jian started up a state-of-the-art crystallization center at J-Star Research in the beginning of 2014 complementing its strong API Process Research. She now leads the Center for Pharma Crystallization at J-STAR as Senior Vice President, addressing a wide range of challenges associated with API isolation from early to late developmental stages. Working closely with drug formulation experts, Jian also has been driving the establishment of drug formulation services at J-Star that are well integrated with API crystallization R&D.
Session 2: Physical Property Based Crystallization Process Development