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Category : PCS2023

Solving Punch Sticking Problems During Tablet Manufacturing Through Crystal Engineering of APIs

By Prof. Changquan Calvin Sun, Ph.D. Professor, University of Minnesota The development of a quality tablet product requires overcoming deficiencies in pharmaceutical properties of tablets to meet several performance...

Stabilization of Amorphous Drugs by Polymers: The Role of C*

By Prof. Ronald Siegel, Professor and Department Head, Department of Pharmaceutics, University of Minnesota, Minneapolis, MN 55455 For many low solubility drugs, the crystalline form is unfavorable due to...

Prof. Ronald Siegel, University of Minnesota

Professor Siegel received his ScD degree in Electrical Engineering and Computer Science from the Massachusetts Institute of Technology (MIT) in 1984. From 1984 to 1998 he was on the...

Enabling Drug Product Performance via Amorphous Solid Dispersion Technique

By Samuel kyeremateng, Ph.D. AbbVie, North Chicago, IL Small molecule solid dosage drug product with the drug in the crystalline state is typically preferred due its more desirable properties...

Dr. Samuel Kyeremateng, Abbvie

Samuel Kyeremateng, Ph.D. is a Principal Research Scientist and Head of the Material Science and Formulation Modeling Group in NCE Formulation Sciences at AbbVie Deutschland GmbH & Co. KG....

Absolute configuration determination of small molecules with X-ray and electron diffraction

By Dr. Bo Wang, Ph.D. Biogen, Cambridge, MA Absolute configuration determination of an active pharmaceutic ingredient (API) is a crucial task in drug development. Tremendous scientific and technical progress...

Dr. Bo Wang, Biogen

Bo Wang obtained his bachelor’s degree in Pharmaceutical Engineering at Southeast University in China. He then completed his Ph.D. study in physical organic chemistry at Kansas State University. After...

Virtual Polymorph Screening and Targeted Crystallization Powered by in silico Solid-state Modeling

By Dedong Wu, Ph.D. Advanced Drug Delivery, PharmSci, R&D, AstraZeneca, Boston US dedong.wu@astrazeneca.com It is challenging and laborious to identify a crystallization process to access an optimal drug substance...

Dr. Dedong Wu, AstraZeneca

Dedong Wu is an associate principal scientist in Advance Drug Delivery at AstraZeneca. He provides expertise in the areas of drug substance form selection, enabling formulation, targeted drug delivery...

Dr. Cheng Yi Chen, Mirati Therapeutics

Cheng received his BS in Chemistry at Xiamen University in 1984 and subsequently continued his Ph.D study at the Ohio State University from 1985-1990.  He single handedly completed the...

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