By Mr. Brian Samas, Pfizer Molecule XXIII is the most experimentally characterized crystal structure prediction (CSP) blind test molecule to date. Crystal structures of five polymorphs are presented with...
By Richard Becker, BlazeMetrics Abstract: Pending
By Dr. Nima Yazdanpanah, Procegence Drug substance isolation by crystallization and filtration and spray drying are last stages of the drug substance manufacturing process, where critical quality attributes (CQAs)...
By Dr. Mike Bellucci, XtalPi Inc Crystallization is the most widely used separation and purification process in the pharmaceutical industry. The resulting crystal structure and corresponding crystal morphology isolated...
By Kevin Roberts, Leeds University The crystallization of organic materials provides a common, energy efficient methodology for the purification and isolation of high value compounds such as pharmaceuticals. The...
By Dr. Yuriy Abramov, Exe. Director of CC&DS, J-Star Research Regulatory expectations for control of impurities in new drugs have been established through ICH guidelines. The most efficient approach...
By Dr. Michal Achmatowicz, Mirati Therapeutics Abstract: A new approach to stereopure atropisomeric molecules is enabled by a continuous flow-crystallization process. Continuous accumulation of the product under its optimal...
By Dr. Simon Bates, Rigaku Americas Corp X-ray powder diffraction has been the gold standard for solid state pharmaceutical analysis for quite some time. However, when it comes to...
Dr. Robert Docherty did his degree and PhD. at Strathclyde University and joined ICI/Zeneca in 1988 where he worked on the solid-state structure and crystallization of dyes, pigments, biocides,...
By Dr. Bob Docherty, Pfizer The focus would be on solid form screen & selection, crystallization process development, pre-formulation evaluations, particle engineering and projecting the API attributes to drug...