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Category : PCS2022

Spherical Cocrystallization of Pharmaceuticals

By Prof. Changquan Calvin Sun, Pharmaceutical Materials Science and Engineering Laboratory, University of Minnesota The development of a quality tablet product requires overcoming deficiencies in pharmaceutical properties of an...

Mr. Brian Samas, Pfizer

Mr Brian Samas is an industrial scientist with over 22 years of experience at Pfizer Inc. Currently he holds a position of Sr. Principal Scientist in the Materials Science...

Five Degrees of Separation: Characterization and Temperature Stability Profiles for the Polymorphs of PD-0118057 (Molecule XXIII)

By Mr. Brian Samas, Pfizer Molecule XXIII is the most experimentally characterized crystal structure prediction (CSP) blind test molecule to date. Crystal structures of five polymorphs are presented with...

Richard Becker, BlazeMetrics

Richard is the Managing Director of Blaze Metrics, a company that designs, develops, and assists their customers to implement and apply cutting edge In-Process Microscopy, Spectroscopy, & Analytics from...

Amorphous or Crystalline? Using Next Generation PAT to Track API Particle Attributes for Enhanced Downstream Processability

By Richard Becker, BlazeMetrics   Process Analytical Technology (PAT) has dramatically expanded its capabilities over the last decade. Today’s PAT enables an in-depth understanding of process behavior on both...

Particle engineering by spray drying: process dev., scale-up, and technology transfer

By Dr. Nima Yazdanpanah, Procegence Drug substance isolation by crystallization and filtration and spray drying are last stages of the drug substance manufacturing process, where critical quality attributes (CQAs)...

Dr. Mike Bellucci, XtalPi Inc

Dr. Michael Bellucci is a Senior Director at XtalPi, Inc. where he leads a research team that develops algorithm technologies for solid form development and risk assessment as well...

Intelligent Cloud-Based Algorithms for Reducing Risk in Crystallization Process Development

By Dr. Mike Bellucci, XtalPi Inc   Crystallization is the most widely used separation and purification process in the pharmaceutical industry.  The resulting crystal structure and corresponding crystal morphology...

A Digital Mechanistic Workflow for Predicting Solvent-Mediated Crystal Morphology

By Prof. Kevin Roberts, University Of Leeds   The crystallization of organic materials provides a common, energy efficient methodology for the purification and isolation of high value compounds such...

Prof. Kevin Roberts, University of Leeds

Kevin Roberts is currently Brotherton Professor of Chemical Engineering at the University of Leeds in the UK where he is also Director of the EPSRC’s Centre for Doctoral Training...

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