By Dr. Nima Yazdanpanah, Procegence Drug substance isolation by crystallization and filtration and spray drying are last stages of the drug substance manufacturing process, where critical quality attributes (CQAs)...
Dr. Michael Bellucci is a Senior Director at XtalPi, Inc. where he leads a research team that develops algorithm technologies for solid form development and risk assessment as well...
By Dr. Mike Bellucci, XtalPi Inc Crystallization is the most widely used separation and purification process in the pharmaceutical industry. The resulting crystal structure and corresponding crystal morphology...
By Prof. Kevin Roberts, University Of Leeds The crystallization of organic materials provides a common, energy efficient methodology for the purification and isolation of high value compounds such...
Kevin Roberts is currently Brotherton Professor of Chemical Engineering at the University of Leeds in the UK where he is also Director of the EPSRC’s Centre for Doctoral Training...
By Dr. Yuriy Abramov, Exe. Director of CC&DS, J-Star Research Regulatory expectations for control of impurities in new drugs have been established through ICH guidelines. The most efficient approach...
By Dr. Michal Achmatowicz, Mirati Therapeutics Abstract: A new approach to stereopure atropisomeric molecules is enabled by a continuous flow-crystallization process. Continuous accumulation of the product under its optimal...
Dr. Michal Achmatowicz received Ph.D. in organic chemistry in 2001 after working with Prof. Janusz Jurczak at the University of Warsaw and the Institute of Organic Chemistry of the...
By Drs. Yuriy Abramov and Shanming Kuang, Center for Pharma Crystallization, J-Star Research Small molecule drug candidates tend to have different solid forms, including anhydrate, hydrate, solvate, salt, cocrystal...
Dr. Shanming Kuang is currently the Head of Center for Pharma Crystallization at Porton Shanghai and Senior Director of Solid Form Studies at J-Stat Research. Shanming obtained his PhD...
